What the Research Found

A Mayo Clinic study examined healthy young adults with no prior exposure to Adderall and found that a single 25 mg dose increased standing heart rate and blood pressure within hours of administration. This wasn’t a tiny effect—the changes were clinically significant.

Here’s what matters most: the researchers specifically noted these findings do not apply to long-term, supervised ADHD therapy. This is a critical distinction that gets lost in the conversation about stimulant medications.