Three Distinct Brain Patterns Emerge

Researchers analyzing brain scans from over 1,100 children with and without attention challenges have identified three distinct “biotypes”—each with its own neural signature. The study, published in JAMA Psychiatry and led by scientists at West China Hospital of Sichuan University along with collaborators from the United States and Australia, found that these patterns go beyond simple behavior observations.

The three profiles include: a severe-combined type with emotional dysregulation, a predominantly hyperactive-impulsive type, and a predominantly inattentive type. Each showed different alterations across brain regions and different patterns of receptors for key brain chemicals. This means the underlying neurology of attention development varies significantly from child to child.